The term " cytochrome p450 " first appeared in literature in 1962 . it was a microsomal membrane - bound hemoprotein without known physiological functions at that time and was characterized by a unique 450nm optical absorption peak of its carbon monoxide - bound form 细胞色素p450这一术语最早于1962年被用于描述一种结合微粒体膜的未知其功能的膜蛋白，因其在450nm处有一特征吸收峰而得名。
